Folha de evidência científica · Judici Cannabis

Cannabis/CBD ajuda no TEPT (estresse pós-traumático)

Canabinoides reduzem sintomas de TEPT (pesadelos, hipervigilância)? — Evidência crescente (esp. em veteranos); nabilona para pesadelos. Ainda emergente, mostrada com os dois lados.

força líquida 0.33 consenso 83 · consenso forte Emergente 28 estudos · 16 apoiam · 4 refutam 100% ≥2020 43% alto nível

📐 Números que convencem

elevated PTC associated with increased state cravings for cannabis (β=0.19, p=0.025)

Associations between posttraumatic cognitions and cannabis cravings among trauma-exposed individuals using cannabis. (2026) · DOI: 10.1111/bjc.70016

reduz severidade dos sintomas de PTSD de 36.2 para 10.5 entre abstinentes

The Effects of Extended Cannabis Abstinence in Comorbid Posttraumatic Stress Disorder and Cannabis Use Disorder. (2026) · DOI: 10.4088/jcp.25m16099

jovens substituem THC por álcool ~14% vs 7.8% em mulheres mais velhas

Predictors of Replacing Alcohol With Cannabis Among Adult Women. (2025) · DOI: 10.7759/cureus.95821

✅ Evidências que apoiam (16)

apoiaCannabis sativa phytochemicals in cancer therapy: molecular mechanisms and therapeutic potential.

Montle R, More GK, Takaidza S, Mtunzi F (2026) · revisao sistematica · força 0.98 · DOI
Cannabinoids exhibit pathway-specific effects, including induction of apoptosis and inhibition of angiogenesis

apoiaCannabidiol: Pharmaceutical formulations and biomedical applications.

Fadavi Eslam A, Mohtashami L, Moghimi P, Iranshahi M (2026) · revisao sistematica · força 0.98 · DOI
CBD mostra potencial terapêutico promissor em várias condições

apoiaTailored psychotherapy and AI-enhanced contingency management for co-occurring disorders in cannabis use disorder: a systematic review.

Mishra S, Mishra S, Rath S (2026) · revisao sistematica · força 0.98 · DOI
melhora sintomas psiquiátricos e reduz uso de cannabis

apoiaEfficacy, effectiveness and safety of medical cannabis in PTSD: a scoping review.

Aviram J, Belobrov R, Grinapol S, Fruchter E (2026) · revisao sistematica · força 0.98 · DOI
reduz pesadelos relacionados ao PTSD em um RCT

apoiaRadical Revelations: The Interplay of Nitrosative Stress, the Endocannabinoid System, and Treatment of Age-Related Disorders.

Davis A, Casmedes IY, Burton MD (2026) · revisao narrativa · força 0.38 · DOI
modulação do estresse nitrosativo e neuroinflamação em doenças neurodegenerativas

apoiaThe Endocannabinoid System in PTSD: Molecular Targets for Modulating Fear and Anxiety.

Lyndon S (2026) · revisao narrativa · força 0.38 · DOI
nabilone alivia pesadelos relacionados ao trauma

apoiaAssociations between posttraumatic cognitions and cannabis cravings among trauma-exposed individuals using cannabis.

Deguzman-Lucero RM, Le JU, Schmidt NB, Short NA (2026) · ensaio clinico · força 0.34 · DOI
elevated PTC associated with increased state cravings for cannabis (β=0.19, p=0.025)

apoiaThe Effects of Extended Cannabis Abstinence in Comorbid Posttraumatic Stress Disorder and Cannabis Use Disorder.

Rodas JD, Sorkhou M, Kloiber S, George TP, Hassan AN (2026) · ensaio clinico · força 0.34 · DOI
reduz severidade dos sintomas de PTSD de 36.2 para 10.5 entre abstinentes

apoiaPreclinical antitumor evaluation of a tetrahydrocannabinol and cannabidiol (1:6) cannabis extract in an MCF-7 xenograft model of estrogen receptor-positive breast cancer.

Meesiripan N, Thanasitthichai S, Sangrajrang S, Suwanpidokkul N, Prayakprom P, Bodhibukkana C et al. (2026) · pre clinico · força 0.33 · DOI
reduz crescimento tumoral em todos os grupos tratados

apoiaCannabis Use and Intimate Partner Violence During Pregnancy Are Associated with Poorer Postpartum Mental Health.

Marvin MJ, Ballinger AL, Stein SF, Fairchild JN, Bogat GA, Lonstein JS et al. (2026) · ensaio clinico · força 0.33 · DOI
cannabis use during pregnancy é associado a PTSD, depressão e ansiedade elevadas

apoiaCannabidiol modulates spontaneous recovery through distinct and conserved transcriptomic signatures in mPFC subregions.

Son M, Song I, Pradeep P, Chang B, Girgenti MJ, Girgenti MJ et al. (2026) · pre clinico · força 0.33 · DOI
reduz recuperação espontânea em modelos de camundongos

apoiaPredictors of Replacing Alcohol With Cannabis Among Adult Women.

Attonito J, Mueller JE, Villalba K (2025) · outro · força 0.33 · DOI
jovens substituem THC por álcool ~14% vs 7.8% em mulheres mais velhas

⚠️ Evidências que refutam (4) — transparência

refutaPosttraumatic stress disorder (PTSD) symptoms, solitary alcohol and cannabis use, and consequences among young adults.

Moskal KR, Traxler SM, Briles E, Miller MB, Teeters JB (2026) · força 0.36 · DOI

refutaClinical Experience and Student Support for Medical Cannabis Use: A Secondary Analysis.

Tong AW, DuBoux CJ, Seuferer RH, Clobes TA, Siu FW, Magana B et al. (2026) · força 0.36 · DOI

refutaCannabinoid use generalizes stress responses: involvement of astrocyte plasticity and activation of matrix metalloproteinases in the nucleus accumbens core.

Hodebourg R, Duncan L, Dereschewitz E, Kalivas P (2026) · força 0.33 · DOI

refutaCannabinoid use generalizes stress responses by altering the astrocyte plasticity through extracellular matrix signaling in the nucleus accumbens core

Hodebourg R, Duncan L, Dereschewitz E, Kalivas P (2025) · força 0.33 · DOI

Folha gerada em 28/09/2026 pela plataforma Judici Cannabis. Evidência real e rastreável (DOI). 8 estudo(s) de contexto (revisões/mecanístico) não listados. Força líquida = apoio − refutação ponderado; maturidade por regras explícitas. Não substitui aconselhamento médico/jurídico.

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